Amidating monooxygenase chicago dating reciprocal
Annotation score:2 out of 5 The annotation score provides a heuristic measure of the annotation content of a Uni Prot KB entry or proteome.
This score cannot be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein. This indicates the type of evidence that supports the existence of the protein.
This subsection of the Names and taxonomy section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry.
Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’. This subsection of the Names and taxonomy section shows the unique identifier assigned by the NCBI to the source organism of the protein.
This is known as the ‘taxonomic identifier’ or ‘taxid’. This subsection of the Names and taxonomy section contains the taxonomic hierarchical classification lineage of the source organism. Each reviewed entry is assigned a unique entry name upon integration into Uni Prot KB/Swiss-Prot. This subsection of the ‘Entry information’ section provides one or more accession number(s).
Using RFLPs, Localization of the peptidylglycine alpha-amidating monooxygenase gene (Pam) introduces a region of homology between human chromosome 5q and mouse chromosome 1. They noted that the NEC1 gene (162150), which encodes another enzyme important in posttranslational processing of neuroendocrine precursors, prohormone convertase 1 (PC1), is located in the same region (5q15-q21). (1994) mapped the Pam gene to mouse chromosome 1 in 3 individual backcrosses.
Mammalian Genome 5: 738-739, 1994.[Pub Med: 7873888]" pmid="7873888" Peptidylglycine alpha-amidating monooxygenase (EC 18.104.22.168) is a multifunctional protein containing 2 enzymes, peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL), that act sequentially to catalyze the alpha-amidation of neuroendocrine peptides. (1990) showed that alternative splicing generates 2 forms of PAM m RNA in humans. (1993) used Southern blot analysis of human placental DNA to demonstrate that PAM is encoded by a single gene. (1992) mapped the human PAM gene to the long arm of chromosome 5.
It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first. The checksum is a form of redundancy check that is calculated from the sequence. It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low. These are stable identifiers and should be used to cite Uni Prot KB entries.
However Uni Prot KB may contain entries with identical sequences in case of multiple genes (paralogs). Upon integration into Uni Prot KB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’. This subsection of the ‘Entry information’ section shows the date of integration of the entry into Uni Prot KB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’).